Pituitary dysfunction

Pituitary gland is the body's most important endocrine gland anterior lobe and posterior lobe divided into two parts. It secretes a variety of hormones, such as growth hormone, thyroid stimulating hormone, adrenocorticotropic hormone, gonadotropin, oxytocin, prolactin, black cell stimulating hormone, etc., can also be stored at antidiuretic hormone secreted by the hypothalamus. These hormones on metabolism, growth, development and reproduction, which are an important role. Pituitary dysfunction etiology is located in the pituitary are known as primary pituitary dysfunction, are located in the hypothalamus called secondary pituitary dysfunction.
We should strive for the cause of treatment.
Objective anterior pituitary hyperthyroidism therapy are: ① inhibition or removal of pituitary synthesis and (or) excessive secretion of pituitary hormones, thereby improving organ function in the body caused by excessive pituitary hormone disorders and metabolic disorders, prevent or slow complications . ② to remove the pituitary tumor or hyperplastic tissue, reducing its impact on the pituitary and (or) the saddle area organized oppression and erosion. Treatment methods are: ① pituitary adenoma or hyperplasia tissue resection, the general route microsurgery transsphenoidal pituitary tumor resection, significantly extended by the amount available on the saddle by way of surgery. ② pituitary radiation therapy, the use of external radiation therapy (deep X-ray and Co-rays has been seldom used, the use of accelerated particles or Proton radiation therapy), pituitary implanted radionuclides such as Au or Yb, because the implant is not easy, and difficult control dose, has been seldom used. ③ neuroendocrine medications, changes in the hypothalamus or pituitary hormone structure, made its agonists or antagonists, available genetically engineered or synthetic polypeptide under hypothalamic-pituitary hormone, to suppress the pituitary synthesis and (or) releasing hormone, such as bromocriptine treatment of high PRL hyperlipidemia, cyproheptadine treatment ACTH tumors and Nelson's syndrome, long-term GnH releasing hormone agonist treatment of central precocious puberty.
Anterior pituitary dysfunction should be complementary and alternative long-term physiological doses of the hypothalamus, pituitary gland or hormone target. When both thyroid and adrenal insufficiency, or at least should first be used simultaneously with thyroid hormone adrenocorticotropic hormone, in order to avoid increasing the basal metabolic rate to promote more adrenal failure. In case of stress, the dosage should be increased, in addition to still symptomatic and supportive therapy should be given, in particular, rapid correction of various metabolic disorders. Ideal replacement therapy is transplantation of endocrine glands, tissues or cells, which needs further study.