In plasma cholesterol and triglycerides are two sources: Exogenous came from food, digested by the small intestine absorption by the body to endogenous synthesis. Triacylglycerol synthesis in the liver and cholesterol mainly in the liver and small intestinal synthesis. The body has a complex feedback mechanisms to regulate cholesterol absorption, synthesis, decomposition and excretion, and maintain its dynamic equilibrium concentration in the blood.
Mainly from serum cholesterol synthesis in vivo, intestinal absorption by the body of the strict regulation and control, not with the consumption of cholesterol is proportional. Such as cholesterol intake per person per day increased 100 mg, serum cholesterol rose by only 3 mg -5 mg / l points. In the synthesis of cholesterol every day about 1.5 grams, the ratio of exogenous cholesterol much higher. Hepatic cholesterol synthesis both places, but also deal with decomposition cholesterol places. When eating too much animal fat (a liver and small intestine cholesterol synthesis of raw materials) or nephrotic syndrome, congenital lipid metabolism disorders, liver metabolism obstacles arise, could result in hyperlipidemia. Other factors, such as mental stimulation, smoking, stress, seasonal temperature changes, menstruation, pregnancy, etc., can cause serum cholesterol level fluctuations.
Lipid and lipoprotein usually increased with the age increased, it is because the elderly lipid and lipoprotein metabolism reduced results. Generally speaking, the 50-year-old male, 65-year-old female, cholesterol and triglycerides will reach its peak. Shanghai 438 elderly lipid and lipoprotein findings: Urban old age group serum lipid was significantly higher than the young group. With the concentration of the elderly lipid weight gain, decreased activity, accompanied by hypertension and coronary heart disease and have increased.
Tuesday, March 25, 2008
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