Tuesday, March 25, 2008

Shaped gland hypofunction caused dyslipidemia will change?

On the one hand, the promotion of thyroid hormone synthesis of cholesterol in the liver, on the other hand promote cholesterol and its metabolites from the bile excretion. Therefore, the effects of thyroid hormone serum cholesterol and the formation of degradation. In other words, the lack of thyroid hormone, although lower cholesterol synthesis, but its speed from the lower total cholesterol concentration in the blood increase. Therefore, in patients with hypothyroidism lipid synthesis and degradation can be used to reduce, the latter mainly, the overall result is a blood lipid concentrations increased, but less significantly higher triglyceride see.
Lipoprotein increased primarily low-density lipoprotein (LDL) levels increased. Some researchers believe that the disease in patients with LDL receptor link defects, LDL and thyroid hormone levels were more obvious negative correlation with the thyroid stimulating hormone level was positively correlated, so LDI can be used as indicators of thyroid function. Pituitary dysfunction secondary to the hypothyroidism, there will be the same lipid change. Increased lipid often appear in Myxedema before. The patients with atherosclerosis may increase in the incidence of hyperlipidemia and relevant.

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