Tuesday, March 11, 2008
Neurogenic tumors
Overview neurogenic tumors, tumors of the mediastinum one of the most common, according to domestic and foreign teams of about 25 reported cases of ~ 50% often occurred in intercostal nerve or spinal nerve roots. Therefore, the vast majority of spinal posterior mediastinum adjacent groove. In histology, according to the Organization of origin is usually neurogenic tumors into three categories : ① origin in the nerve sheath cells. a schwannoma, neurofibroma and malignant schwannoma. ② origin in the nerve cells, such as paraganglioma. ganglion mother cell tumors and neuroblastoma; ③ originated from the Vice ganglion cells. Such as Vice ganglioneuroma. Most schwannomas, including schwannoma, neurofibroma, originated in highly differentiated mature Schwann (Schwann)'s cells, usually benign. These tumors were round in shape, and a complete capsule. Intraoperative findings were coated with tumor tissues and organs around the outer membrane attachment is not solid. About 10% of mediastinal neurogenic tumors is often extended to the intervertebral foramina, resulting in some tumor growth in the spinal canal, This so-called dumbbell-shaped tumor approximately 2 / 3 of the cases originated in the nerve sheath. Neurological symptoms of vertebral Kong and the expansion of cases should be held before myelography. In a typical benign schwannomas, surgical resection have no difficulties, However, dumbbell-shaped schwannoma need thoracic surgery and neurosurgery doctor completed. In mediastinal tumors, about 30% of malignant transformation eventually happen. In malignant tumors, mainly nerve fibers sarcoma and neuroblastoma. Where an envelope benign mediastinal tumor, surgery can more thoroughly removed. Generally benign neurogenic tumors, clinical more asymptomatic, but in a haphazard investigation body was found a few cases of self chest pain, chest tightness and shortness of breath, on the main diagnostic X-ray examination.
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