Hyperlipoproteinemia How did it happen?

Hyperlipoproteinemia according to the reasons for the onset is usually divided into two categories, namely primary and secondary Hyperlipoproteinemia of Hyperlipoproteinemia.
Primary Hyperlipoproteinemia also known as familial Hyperlipoproteinemia, to do more to congenital genetic disease, there are family history is the result of lipid and lipoprotein metabolism congenital defects, and certain environmental factors (such as diet , nutrition and drugs, etc.), by unknown mechanisms arising. All five types of Hyperlipoproteinemia can for the family, and may be representative of many different changes. In recent years, I believe that familial type Hyperlipoproteinemia with cell surface low-density lipoprotein (LAL) receptor decreased (found in the different types of) or absent (found in the same type of homozygous), and LDL can not enter the cells within the normal speed and metabolic disease.
Secondary Hyperlipoproteinemia incidence of the disease in some of the pathology on the basis of certain drugs or caused by the abnormal lipid metabolism, and clinical manifestations of the characteristics of the primary disease or useful special drug history, and with increased blood lipids. If the control of diabetes, hypothyroidism and myxedema, nephrotic syndrome, both inside and outside the liver bile duct obstruction, pancreatitis, abnormal hypergammaglobulinemia, gout, alcoholism and use of contraceptives, such as female.