What is liver cirrhosis caused by bleeding?

Epistaxis, gingival bleeding, and skin purpura, siltation grouper, bleeding esophageal varices, and so is cirrhosis, liver dysfunction, a common complication coagulation disorder. Bleeding in patients with liver cirrhosis is often critical condition performance. The need for active treatment. The reason for the hemorrhage occurred:
① clotting factor to reduce production.
② and decrease in the number of platelet dysfunction: platelet hemostatic process in the whole occupies an important position, the decline in the quality and quantity are not conducive to stop bleeding. Often accompanied by severe cirrhosis and splenomegaly hypersplenism, a large number of platelet stranded spleen, speed up the destruction. Another function of the bone marrow, liver cirrhosis inhibition may also reduce the number of platelets, dysfunction.
③ anticoagulant substances increased: the anticoagulant heparin is an important material, but can be heparanase decomposition, lost its role of anticoagulation. Cirrhosis of the liver enzyme reduce heparin, heparin increase blood circulation, blood coagulation difficult.
④ Fibrinolysis increase: coagulation process is the final stage of formation of fibrin, fibrin fibers can be dissolved by the protease. Cirrhosis, the liver can not effectively remove the fiber-activator, thus increasing the dissolution of the fibrin.
⑤ vascular injury: liver cirrhosis vascular endothelial injury, easily capillary permeability increase in bleeding. Cirrhosis also due to increased portal pressure, and esophageal varices, susceptible to injury and bleeding.
⑥ disseminated intravascular coagulation: liver cirrhosis monocyte-macrophage system dysfunction, can not effectively remove procoagulant material, coupled with vascular endothelial damage, activation of coagulation system, in a wide range of intravascular coagulation, need to consume a large amount of platelets and coagulation factor can be induced coagulation disorder. At the same time can be induced coagulation secondary fibrinolysis enhanced, allowing blood from hypercoagulable state into a low hypercoagulable state and bleeding occurred.