Type Ⅱ Hyperlipoproteinemia What are the clinical manifestations?

Giant Hyperlipoproteinemia also called familial hypercholesterolemia is dominant genetic disease. Comparison of this type Most of the major clinical manifestations are as follows:
⑴ xanthoma, eyelid can occur in the Department of performance for the eyes around a yellow spot, known as the yellow eyelid tumor. May also occur in the muscles licensing, for example, in the elbow, muscle residence with a hummocky uplift, known as the tendon of yellow. In addition, the section can also be found in the skin-yellow tumor occurs in the skin vulnerable to oppression, such as the knee, elbow and suffered lacerations in the side of God. Sometimes seen at the crease fingers and the palm of your hand. ⑵ early atherosclerosis, about 60% of the cases in the past 40 years that have angina, and other manifestations of atherosclerosis. ⑶ lipid corneal arch.
Ⅱ a Ⅱ b-type and the clinical manifestations similar, but its biochemical characteristics is different. Ⅱ a plasma-placed appearance fully clarified, the content of cholesterol, triglyceride content of normal, cholesterol / triglyceride ratio> 1.5; Ⅱ b-type look at the majority of plasma clarification, but there are also a few slight turbidity, cholesterol and triglycerides 3 ester at the same time increased cholesterol / triglyceride ratio uncertainties.