True hermaphroditism and infertility.

Ovarian is gonad organs, in view of child-bearing age, ovarian 2.5 ~ 5.0 cm long, 1.5-3.0cm wide. 0.6 ~ 1.5 cm thick. In normal ovarian within ovarian Waterloo. Ovarian the main function is generated and discharged egg, and steroid hormone secretion. If ovarian syndrome, or dysfunction of tumor, etc. affect human development, such as health and fertility. True hermaphroditism hermaphroditism is due to abnormal gonadal development, true hermaphroditism is patients with ovarian and testicular two gonad also exist. According to reports can have the following three conditions : ① side of the ovary and testis to the other side, about 40%; ② side of the ovary or testes, on the other side of ovotestis, 40%; ③ both bilateral ovotestis. both fibrous tissue between intervals, or about 20%. 【Clinical manifestations -- genitalia were to be male-female or mixed type, but the male type frequently, about 2 / 3. Newborn baby care and more common cryptorchid and hypospadias. Female genital - who was accompanied clitoral hypertrophy, in both breasts after puberty development, but may face a male sign, the majority of the uterus, but more with hypoplastic or abnormal, more than half a cyclical menstrual or hematuria. Check gonad visible male and female gonad two, but imperfecta. 【Auxiliary -- karyotype can be different karyotype, 46, XX or about 50%, 46, XY rare; may 46, XX/46, XY; 46, XY/45, XO as mosaicism. Experiments prove ovotestis Organization of the H-Y antigen (+) / H-Y antigen chimera, testicular tissue from the cells of the H-Y (+), ovarian tissue from the cells of the H-Y (-), 46. XX true hermaphroditism individual Sxr with autosomal genes. Pathologic examination confirmed the same time see the ovary and testis. 【Treatment -- the principle is to prevent the removal of malignant testicular tissue. individual patients (uterine) in testicular tissue resection after menstruation ebb and have normal reproductive capacity. Surgery should carefully distinguish between ovary and testis, ovary removed testicle retained, as indeed difficult to distinguish, for the sake of safety removed all the gonad. More general surgery by women to be corrected.