Monday, March 17, 2008

Sepsis patients with cirrhosis

Cirrhosis is the aforementioned intestinal edema, congestion, mucosa variability, increased permeability of flora and abnormal distribution of the quality of factors such as changes in the intestinal bacteria from the gut into the blood circulation favourable conditions and opportunities, can occur bacteria hyperlipidemia. On the other hand, liver cirrhosis, to change the structure and function of bacterial filtration function weakened, and the establishment of liver lateral branches cycle, from the intestinal bacteria portal vein blood can bypass the liver into the systemic circulation, thereby cirrhosis bacteremia continued tendency. Once the immune ability to further reduce or when further enhance the activity of pathogenic bacteria, the bacteria in the blood of long sound operation can cause sepsis. General rapid onset of the disease, condition, the change faster. Shivering with more high fever, irregular heat, in more than 390 C-40OC. Systemic symptoms were often visible headache, muscle pain, respiratory acceleration, speed up the heartbeat, such as performance, change is often thought, light, drowsiness, hallucinations, coma, heavy. Its diagnostic criteria: 1, chills fever; 2, shock; 3, with the bacterial peritonitis or other parts of bacterial infection; 4, increase in short-term liver disease, all jaundice or a liver coma deepened; 5, peripheral leukocytes and neutrophils increased, particle and nuclear poisoning the left; 6, blood or bone marrow-positive bacterial culture. 5, with the former at least one and six who can be confirmed.

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