perlipoproteinemia clinical performance

Type IV Hyperlipoproteinemia very clinical especially common after the age of 20 at the onset, for the family, was dominant. Its characteristics are endogenous triglycerides abnormal increase may be due to increased synthesis of the liver, or the surrounding tissue removal weakened. The main clinical manifestations : muscle cells xanthoma, subcutaneous tumor nodules yellow, yellow skin rash kind of eyelid tumors and tumor yellow spot; Lipid retinal disease; The rapid progress of atherosclerosis; can be associated with pancreatitis, increased blood uric acid; Most have abnormal glucose tolerance. Biochemical characteristics : appearance placed plasma clarification or turbidity but no chylomicrons top; Triglycerides increased significantly, Most cholesterol and normal or slightly elevated cholesterol / triglyceride ratio uncertainties.