The pathological changes of renal cell carcinoma

Single often unilateral renal cell carcinoma lesions, about the incidence of side similar to the majority of renal cell carcinoma round, size, a great disparity. No histological tumor capsule, but there are oppressed and the renal parenchyma tissue fibers into the false capsule, a small number of yellow or brown uniform, the majority of hemorrhage, necrosis, fibrosis plaque, and bleeding can be formed cystic necrosis , itself a papillary cystic carcinoma. All tumor can damage kidneys, and violations of the neighbouring fat, muscle, blood vessels, lymphatics, renal fascia around is to prevent a partial diffusion barrier layer. RCC easy to expand the formation of venous thrombosis, can be extended into the renal vein and inferior vena cava. Common lung metastasis to the brain, bone, etc.. Electron microscopic examination see the majority of renal cell carcinoma showed varying degrees of proximal tubules of the ultrastructure that occurred in kidney proximal tubules. The majority of renal cell carcinoma clear cell carcinoma, also at the same time, or the majority of granulosa cells, such as spindle-shaped cells, and sometimes resembles sarcoma, the greater the degree of malignancy of the kidney, known as undifferentiated carcinoma.