Sunday, March 2, 2008
Ovarian Sex Cord Stromal Tumors
1. Particles a stromal tumors : By the nature of the cable granulosa cells and stromal components and derivatives fibroblast cells and egg membrane composition, a single component or two of the organization's elements coexist, and sub-degree varies. (1) granulosa cell tumor is functional most common tumors, malignant tumors of low - to 50-year-old women are most common. Who can secretion of estrogen, it is feminine, pre-pubescent, there will be false precocious puberty, menstrual childbearing age to cause disorder in postmenopausal women have endometrial hyperplasia, or even cancer, and tumors of the unilateral, sizes, surface smoothness or lobulated, solid plane, half of cystic change. Generally good prognosis. Five-year survival rate of 80%. A few of these cases for years after treatment relapse fair that there should be long-term follow-up. (2) theca cell tumor incidence rate of granulosa cells of 1 / 2, are essentially benign, but there are 2 to 5% of the malignant. Occur in postmenopausal, rare before the age of 40. Unilateral tumor size is not generally middle-size, rolling hard, smooth surface, the cross-section of solid, gray, the typical person with yellow lipid area. The tumors can be more secretion of estrogen, the feminization of symptoms compared with granulosa cell tumor significantly. Often associated with endometrial hyperplasia or endometrial cancer. Theca malignant tumor infiltrating directly adjacent tissues and may distant metastasis, but the general prognosis of ovarian cancer is still better. (3) ovarian fibroma of solid tumors were more common, accounting for ovarian tumor 2 to 5%, which was benign, was particularly prevalent in middle-aged women. Tumors of the unilateral, middle, smooth surface or nodular, gray and white plane, substantive, very hard. Occasionally fibroids with pleural effusion or ascites, said Marcos syndrome, surgical resection after Hydroperitonia go away. Ascites by diaphragmatic lymph channels or channel seepage to chest, the side separated lymphatic rich, it hydrothorax occurred in the right side. 2. Support a stromal tumors : Also known as testicular cells. Rare occurred in the following 40-year-old young women, mostly benign, with the masculine role, a small number of endocrine function, or without showing feminization. 10 ~ 30% were vicious acts, the five-year survival rate of 70 ~ 90%.
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