Sunday, March 9, 2008
Ovarian cancer clinical performance
Ovarian cancer can occur at any age, 2 / 3 above occurred in 40-65 years. Initially has no other symptoms, but a fast-growing, easy-proliferation, once found, often already advanced disease, therefore, So far ovarian cancer five-year survival is only 25% Series -30%. In the reproductive tract cancer, ovarian cancer accounts for 22.9%, second only to cervical cancer, endometrial adenocarcinoma, the death of over two series. for the first gynecologic malignancies. [Clinical] generally asymptomatic early, but fast-growing, in the short term, there may be symptoms. Pelvic have started to fall flu, stomach or indigestion, nausea; Advanced will have ascites, abdominal pain, the lower abdomen and irregular palpable mass, and many of solid inactive, or to cachexia. Tumors with endocrine function, there will be the sexual precocity, menstrual disorders, such as postmenopausal out. [Diagnosis] 1. With the above symptoms. 2. Abdominal examination : can touch irregular mass, or ascites. If so distant metastasis, can be found on the collarbone, armpit and superficial inguinal lymph nodes and lung real change and signs of pleural involvement. 3. Gynecological examination : touching mass usually bilateral, substantive or cystic, irregular in shape, with the surrounding tissue adhesions fixed, After the dome often touched on fixed nodules, no tenderness. Serious cancer can be filled with the entire pelvic was "frozen" - like pelvis. 4. B and G-examination : pelvic masses can suggest the nature, location and size, and pots of abdominal viscera. 5. Cytological examination : through vaginal cytology, the posterior vaginal fornix puncture, pumping ascites tumor puncture method to find subjects such as cancer. 6. Laparoscopy : the extent of the lesion may look and may make tumor biopsy. 7. Abdominal x ray examination : The diagnosis of teratoma. Gastrointestinal imaging can clearly gastrointestinal tumor and the relationship. 8, biochemical assay (1) immune diagnosis : Determination of CEA, AFP, HCG, CA1252, CA : 19-10 months, and other tumor markers useful for the diagnosis. (2) or ascites serum alkaline phosphatase, lactate dehydrogenase, blood urea nitrogen, serum cholesterol, total bilirubin and total protein, etc. increased. 9, clinical stage Phase I : ovarian tumor stem limitations. Ia : tumor confined to the ovary, no ascites. Ib : bilateral tumors confined to the ovary, no ascites. Ic : work, work or b ascites or peritoneal fluid found in cancer cells. Phase II : unilateral or bilateral ovarian tumors, pelvic proliferation. Ⅱ a : uterine Instillation transfer or jurisdiction. II b : has been transferred to the pelvic other organizations. Ⅱ c : a II or II b of the peritoneal fluid or ascites find cancer cells. Phase III : peritoneal metastasis, such as the intestines, omentum, the liver and subphrenic or retroperitoneal lymph node metastasis. Ⅳ : distant metastasis, such as the lungs, mediastinum, such as the lymph nodes under the collarbone. 10. Differential diagnosis (1) Endometriosis : There's increasing sexual dysmenorrhea, infertility and other history, After hormone therapy can ease symptoms and reduced mass. (2) Pelvic Inflammatory Mass : long course and light conditions and tenderness Obviously, the anti-inflammatory therapy. (3) pelvic tuberculosis : According to bite and history test, be able to identify super-8, effective anti-tuberculosis treatment.
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