How to detect early liver cirrhosis?

Early cirrhosis not obvious clinical manifestations can be asymptomatic or only mild symptoms, such as fatigue, poor appetite, indigestion, nausea, vomiting, right upper quadrant pain, diarrhea and. No characteristic symptoms, and gastrointestinal tract diseases in general there are not specific to early liver cirrhosis, so difficult to simply relying on early detection of symptoms. Early in the medical cirrhosis, liver enlargement often, in some cases enlarged spleen, and liver palms Zhizhuzhi visible. Liver function tests and more in the normal range or mildly abnormal protein is the more prominent aspects of the change, such as reducing albumin, globulin increased, white, or even close globulin ratio inversion. Well, what other tests can be found early cirrhosis? 1. Indicators is the best for the patients to live a transhepatic pathological examination. Using a second puncture, take the small amount of liver tissue under the microscope inspection, whether liver fibrosis and connective tissue formation.
2. Do B-scan. In the early liver cirrhosis, can be found hepatomegaly, hepatic echo showed increased thickening. Once the development of advanced, portal wider than 13 mm diameter, splenic vein widened more than 8 mm, thickness spleen, liver narrow, the liver surface is not smooth, rugged, accompanied ascites.
3. Blood inspection four fibrosis serological indicators. Hyaluronic acid (HA), laminin (LN), type Ⅲ collagen (P Ⅲ P), collagen type Ⅳ (C Ⅳ). 2 ~ 3 is significantly higher, consider early cirrhosis.