Hepatic coma thing is how

Hepatic coma known as hepatic encephalopathy is the result of serious damage to liver function, blood can not be toxic metabolites detoxification, or a portacaval shunt after, the natural formation of collateral circulation in the portal vein bypass the toxic substances in the liver, liver detoxification and without direct access to the processing of the cycle, metabolic disorder arising from the central nervous system, as time passes, there sleepiness, confusion, coma. Now that the pathogenesis of hepatic encephalopathy with the following factors:
Ammonia poisoning theory; Only trace normal blood ammonia, does not exceed 0.1 percent mg, when more than 5 percent mg alone poisoning when the risk of death. The causes of elevated blood ammonia: ① cirrhotic patients due to the decomposition of protein absorption incomplete, produced a considerable amount of ammonia. ② because of portal hypertension caused by the short circuit doors inferior vena cava, a large number of liver detoxification inactivated without ammonia, and other toxic elements directly into the systemic circulation. ③ intestinal protein catabolism process, the role of amino acid by amino from the ammonia, the liver disease can not be completely removed. Elevated ammonia through the blood-brain barrier into the brain tissue, the brain tissue of ammonia in too high, it interferes with glucose oxidation process, the brain tissue caused by the energy shortage, the brain being unable to maintain their normal function, resulting in nerve Ma addiction, sleepiness, insanity, until the development of a coma.
And the other related to the pathogenesis of hepatic coma factors are mercaptan doctrine, neurotransmitters false doctrine, such as other metabolic disorders.
Hepatic coma with other diseases caused coma phase identification, such as: central nervous system infection, cerebrovascular accident, diabetic coma, low blood sugar coma, uremia, electrolyte imbalance and tranquilizers such as excessive.