Henoch - Schonlein purpura

Henoch - Schonlein Purpura (allergic purpura) is a common vascular hemorrhage allergic diseases. Because the body is sensitized to certain allergic substances, widely vasculitis. small artery and capillary permeability, brittle, with exudative hemorrhage, edema. The main clinical manifestations of skin purpura, mucosal bleeding also can be accompanied by skin rash, joint pain, abdominal pain and renal damage. Of the disease in children and adolescents were seen, more men than women, most of the incidence spring and autumn. [Cause -- the direct cause of the disease is often difficult to determine, the factors are : 1. Bacterial infections (beta hemolytic streptococcus caused by upper respiratory tract infection the most common, apart from Staphylococcus aureus, Pneumococcal, TB), HIV (rubella, chickenpox, measles, influenza) and intestinal parasites. Second, food fish, shrimp, crab, eggs, milk and other food heterosexual protein. 3, antibiotic drugs (green, chain of red, chloramphenicol), sulfonamides, isoniazid, antipyretic analgesics (salicylic acid, Phenylbutazone, quinine, etc.). 4, the other cold, pollen, grave-sweepers should always, vaccination. These factors antigen-antibody complex reaction, the complex deposition in the vascular wall or glomerular basement membrane. and the activation of complement and release - such as allergies, damage capillaries, arterioles and capillaries caused extensive Yan, even necrosis of small arteries, the vascular wall permeability and brittleness increased, resulting in subcutaneous tissue, mucosa and visceral organ hemorrhage, edema. Gastrointestinal tract and joints such as a similar change. Kidney disease focal light for many nephritis, a serious can of glomerular capillary focal necrosis or renal involvement. Some scholars believe that the disease is a rapid-onset allergic reaction, a large number of IgE. Adsorbed on the mast cells, which release of bioactive substances caused the damage. [Symptoms of the disease -- the performance of the clinical manifestations : 1-3 weeks before the onset common upper respiratory tract infection. The first disease to the most common skin purpura, in a few cases Purpura before the festival, abdominal pain, low back pain, or hematuria, and mean. According lesions usually are part of the clinical manifestations are divided into the following types. 1, the most common type Purpura, in the dermis layer capillaries and small arteries aseptic inflammation characterized vascular wall can be focal necrosis and platelet thrombosis. Most of the blockage recurring skin, ecchymosis as the main performance, the most found in the lower extremities and buttocks, symmetric distribution, appeared in batches, Stasis point size, and which was purplish red, blended into a slightly higher unit or skin surface. Was bleeding papules or small shape measles, with a slight itching. Will be serious blood-tinged fusion at National Cheng Kung University, the center was haemorrhagic necrosis. Stasis, bruises in a few days gradually dissipated, or recurring, a few cases, with eyes the face, lips, hands, feet limitations angioedema. 2, abdominal (Henoeh purpura) for the performance of major abdominal pain, or in umbilical around the lower abdomen, Colic appearing paroxysmal or persistent pain, with nausea, vomiting, diarrhea and bloody stool. As gutsy serous secretion into the wall, resulting in submucosal edema, hemorrhage, caused irregular bowel motility can induce intussusception. - If the symptoms occur in the skin purpura before easily misdiagnosed as acute abdomen. 3, joint type (Schonlein purpura), joint swelling and pain on, more common in the knee and ankle joints, and other large, intra-articular effusion can, but not septic. Recurrent pain, were migratory, with red, swollen and dysfunction, generally dissipated within a few months, fluid absorption after leaving deformities. If in purpura before easily misdiagnosed as rheumatoid arthritis. 4, kidney - Schonlein purpura -- also known as purpura nephritis, more common in teenagers, often in the emergence of a purpura week, Occasionally until 7-8 weeks. Performance of proteinuria, hematuria, the tube urine, sometimes accompanied by edema, generally within a few weeks and also had recurrent seizures, the long delay of a few persons. A few even involved the entire kidney disease and the development of chronic nephritis with nephrotic syndrome or individual occurrence uremia. 5, and mixed rare type of the above - if the clinical manifestations of the above two species exist, it was mixed. Which while abdominal and joint-type symptoms as Henoch - Schonlein purpura. Other lesions involving the central nervous system, respiratory symptoms, there may be a corresponding minority will have optic nerve atrophy. Iritis or conjunctiva, retinal hemorrhage. Diagnosis of the disease is the principal basis of skin purpura, some patients capillary fragility test positive. Bleeding, clotting time, platelet count, blood clot retraction test and bone marrow examinations are normal. If the merging of infected total increase of leukocytes; When infected with parasites eosinophils can be increased. kidney involvement may have hematuria, proteinuria, or urine tube; Intestinal involved when fecal occult blood positive until blood. Of the disease in Chinese medicine is "spot", "rash" and "Cavity" areas. Most are due to low blood introduces heat caused, but also has Taeatment like. Performance of a febrile illness, using Qingrejiedu, Liangxue Yangyin, such as bleeding Xiaoyu; Performance deficiency - syndrome, the use of vitality, nourishing, Jianopiningchang heart, liver and kidney nourishment, both wind-heat, heat and humidity appetite should Added Shufeng Qingre and Huashi's goods.