Tuesday, March 11, 2008
Guillain-Barre Syndrome
Guillain-Barre syndrome is an acute onset to the nerve root, peripheral nerve damage mainly, associated with CSF protein-cell separation syndrome characterized. Also known as Guillain-Barre syndrome. And the men and women of any age can become ill, but men were seen in young adults. Etiology and pathogenesis has not been fully explained, it is generally thought that with the onset before nonspecific infection and vaccination history, caused by the delayed hypersensitivity immune diseases, the main lesion is peripheral nerve extensive segmental inflammatory demyelinating. The clinical symptoms 1-4 weeks before the onset of upper respiratory tract or a gastrointestinal infection history, or a history of vaccination. Four Seasons may develop the disease, in summer and autumn to be. The clinical characteristics of infectious diseases in after 1-3 weeks, the sudden intense pain to the nerve root (neck, shoulder, waist and lower extremities more), acute sexual symmetry of limb paralysis, the subjective sensation, tendon reflexes weakened or disappeared mainly disease. Concrete expressions (1) movement disorders : limbs and trunk muscle paralysis is the main symptom of the disease. Generally from lower limbs, muscle gradually spread to the trunk, upper limbs and cranial nerve, from side to the other side. Usually 1-2 weeks to peak condition. General paralysis of the proximal distal more important, hypotonia. If breathing, swallowing and pronunciation involvement, can cause respiratory paralysis autonomy, and the pronunciation difficulties swallowing and endangering lives. (2) sensory dysfunction : general lighter, more from the ends of the limbs are numb and began acupuncture flu. May have felt like Motao diminish or disappear allergies, and spontaneous pain, tenderness to the gastrocnemius muscle and the anterior angle obvious. Segmental or occasionally visible beam sensory transduction obstacles. (3) Launching obstacles : limbs tendon reflexes are diminished or disappeared symmetry, abdominal, cremaster reflex normal. Few patients can suffer vertebral beam arising pathological reflex levy. (4) autonomic dysfunction : an initial recovery often sweating, a strong smell Khan, may be sympathetic stimulation by the results. A few patients initial short-term urinary retention. As the disclaimer may bladder function of the autonomic imbalance temporarily or disclaimer about expanding outside of the muscle damage caused by spinal nerve; The stool secretary node; Some patients may appear unstable blood pressure, tachycardia and abnormal ECG. (5) cranial nerve symptoms : 50% of patients with cranial nerve damage to the tongue, pharynx, Vagus nerve, and one side or both sides of the facial nerve paralysis was mostly peripheral. Followed by eye movement, pulleys, the abducens nerve. Occasionally papilledema may be to the optic nerve itself, or inflammatory changes caused by cerebral edema, and probably the protein in cerebrospinal fluid were significantly higher, obstruction of the arachnoid villi, the impact of CSF absorption. According to the diagnosis of infectious disease after disease is sudden symmetry of the distal extremities feeling sports and nutrition obstacles tendon reflexes disappear and can be diagnosed. Western medicine to treat the disease causes stress treatment, and treatment of dehydration, nutrition nerve symptomatic treatment. Chinese medicine is that the disease "WeiZheng" areas. Due to its cause more summer-heat and dampness, heat and humidity; Disease is humid Meridian aggression prostitution trial of flaccid, lack of splenic injuries hepatorenal three dirt, result-blood loss, musculo-skeletal disorders, their treatment to more Qingre Lishi, Runzao methocarbamol, HUOXUETONGLUO, ther.use, nourishing the liver and kidney. Bush Essence atrophy of the method.
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