Fisheer's syndrome

Also known as outlined, eye muscle paralysis - ataxia-deep reflection disappeared syndrome; Acute disseminated cerebral spinal nerve root syndrome. Etiopathologic etiology and pathogenesis is not very clear, that the virus infection and allergic two arguments. May also be abnormal or atypical Guillian-Barre syndrome. Clinical manifestations of the disease was mostly young adults, the incidence of male than female double, Most respiratory infections or gastrointestinal disease precursor, in the last two days to a few weeks after the appearance of neurological symptoms, often happens first extraocular muscle paralysis and ataxia, and the final disappearance of deep reflection. (1) extraocular muscle paralysis for many on both sides, and 1 / 3 of cases of eye muscle paralysis, in the course of disease also can be seen gaze palsy, pupillary light reflex anti-regulation and disappeared, suggesting midbrain and pons damage. Normal eyesight and vision. (2) of ataxia more symmetrical ataxia, showing muscle tension reduction, intention tremor, Intermittent speech, nystagmus, sensory dysfunction absent or mild. Cerebellum or suggest cerebellopontine beam, the beam spinal cerebellar damage. (3) deep reflection disappeared more transient deep reflection disappeared. Differential diagnosis (1) of subacute sclerosing panencephalitis (subacute sclerosing panen cephalitis) is a slow viral encephalitis, caused by the measles virus. Children below 12 years of age the most vulnerable to disease, onset implicit attack was carried out, usually in a coma late, the course is longer, up to several months. In the spirit of the early symptoms, there is a medium-term involuntary movements of the special symptoms occur gradually after the mid-limb rigidity, coma, cranial nerve palsy symptoms, physiological hyperreflexia, and their symptoms appeared. CSF IgG, IgM have continued to increase and the curve of plastic-paralysis. Serum and cerebrospinal fluid of measles virus antibody titers increased. (2) acute disseminated encephalomyelitis (acute diseminated encephalomy elitis) is a group in certain infections (especially visiting disease) after the central nervous system demyelinating disease, it is generally thought that with the autoimmune mechanism. The disease of children and young adults to progress to more extensive lesions involving the brain and spinal cord. Sharp onset, the more the infection after 4 ~ 30 days of clinical symptoms, often fever remission again fever, may have dizziness, fatigue, body ache and back stiffness flu symptoms, we can see meningeal irritation. Further development of illness, occur in different degrees of substantive nervous system symptoms, including brain, spinal cord, cranial nerve and / or spinal nerve root damage performance. (3) Multiple Sclerosis (multiple sclerosis) is a young, the prime period of the central nervous system demyelinating diseases. characteristics of lesions disseminated in the course of disease often relapse and remission occurs repeatedly. Lesion site of the different clinical manifestations can be varied. The symptoms often a language barrier. Cranial nerve dysfunction to the ball after neuritis as the first symptom styles. Nystagmus is one of the common symptoms, for horizontal, rotating or vertical. Back, thighs often numb constrictions flu and pain, there will be cerebellar ataxia and sensory. Visibility late spastic paraplegia.