Clinical manifestations of early cirrhosis

Early cirrhosis means no specific clinical signs or symptoms, No significant liver function test abnormalities, but in liver histology, pathological changes have been obvious. Domestic and foreign studies have confirmed that patients with early cirrhosis, liver various increases in both collagen content, with I, III mainly increased collagen deposition. Type I advanced cirrhosis with increased mainly dominated early to III, with the progress of liver fibrosis, I / III collagen ratio from 1 to 1.59, type I collagen fibers increased participation in the formation of connective tissue its reversible strong, mainly seen in advanced liver cirrhosis.
As early cirrhosis in the absence of any specific clinical signs and symptoms, so in a sub-clinical stage of the pathological changes, but some patients can have the following performance.
(1) systemic symptoms: a major weakness, easy fatigue, physical decline. A small number of patients, there will be facial pigmentation.
(2) chronic dyspepsia symptoms: Fresh satisfied that may be associated with constipation or abdominal distension, diarrhea or liver pain, exhaustion after the obvious.
(3) signs: a small number of patients that, mild to moderate swelling of the liver, was particularly prevalent in patients with alcoholic liver cirrhosis, generally without tenderness. Spleen may be normal or mildly swollen.
The clinical manifestations and often easily confused with the original or chronic liver disease patients do not arouse the attention.